BLM Helicase Ortholog Sgs1 Is a Central Regulator of Meiotic Recombination Intermediate Metabolism

Arnaud De Muyt, Lea Jessop, Elizabeth Kolar, +4

Molecular Cell

ChromatinCell DivisionGeneticsMeiosisMolecular Biology +9

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

Franklin L. Zhong, Sharon A. Savage, Marina Shkreli, +6

Genes & Development

Genome InstabilityTelomerase TraffickingSomatic VariantGenetic DisorderGenetics +10

Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I

Rosemary K. Clyne, V.L. Katis, Lea Jessop, +4

Nature Cell Biology

ChromatinDevelopmental BiologyCell RegulationCell DivisionMedicine +12

Meiotic Chromosome Synapsis-Promoting Proteins Antagonize the Anti-Crossover Activity of Sgs1

Lea Jessop, Beth Rockmill, G. Shirleen Roeder, +1

PLoS Genetics

Sgs1 MutationGeneticsGenomic MechanismMolecular BiologyMolecular Genetics +14

Mus81/Mms4 Endonuclease and Sgs1 Helicase Collaborate to Ensure Proper Recombination Intermediate Metabolism during Meiosis

Lea Jessop, Michael Lichten

Molecular Cell

Mus81/mms4 EndonucleaseGenome InstabilityCell DivisionNatural SciencesGenetics +9

Burden of Nonsynonymous Mutations among TCGA Cancers and Candidate Immune Checkpoint Inhibitor Responses

Leandro M. Colli, Mitchell J. Machiela, Timothy A. Myers, +3

Cancer Research

Nonsynonymous MutationsCheckpoint Inhibitor TreatmentImmunologyImmunoeditingPathology +14

Landscape of Combination Immunotherapy and Targeted Therapy to Improve Cancer Management

Leandro M. Colli, Mitchell J. Machiela, Han Zhang, +5

Cancer Research

Whole-exome sequencing and functional studies identify RPS29 as a novel gene mutated in multicase Diamond-Blackfan anemia families

Elizabeth R. Macari, Lea Jessop, Steven R. Ellis, +14

Blood

Infrequent Co-conversion of Markers Flanking a Meiotic Recombination Initiation Site in Saccharomyces cerevisiae

Lea Jessop, Thorsten Allers, Michael Lichten

Genetics

Infrequent Co-conversionGeneticsGenomic MechanismMolecular BiologyMolecular Genetics +15

Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41

Pierre Bigot, Leandro M. Colli, Mitchell J. Machiela, +8

Nature Communications

Renal PathologyImmunologyPathologyCancer BiologyTumor Biology +14