Gary E. Landreth

ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models

Paige E. Cramer, John R. Cirrito, Daniel W. Wesson et al. · Science · 2012 · 1K citations · Full text

ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar et al. · Neuron · 2008 · 854 citations · Full text

Alzheimer's Disease, Biochemistry, Medicine +10

β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis

Colin K. Combs, J. Colleen Karlo, Shih-Chu Kao et al. · Journal of Neuroscience · 2001 · 721 citations · Full text

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

Taylor R. Jay, Crystal M. Miller, Paul J. Cheng et al. · The Journal of Experimental Medicine · 2015 · 674 citations · Full text

CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation

Erin G. Reed-Geaghan, Julie C. Savage, Amy G. Hise et al. · Journal of Neuroscience · 2009 · 594 citations · Full text