Deena Waddleton

Statistics

Publications

Citations

629

H-Index

Active since

1995

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Merck Canada Inc. (Canada)

Memorial University of Newfoundland

Deena Waddleton is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in life sciences, pharmacology, and signal transduction.

Publications per year

1995–2011

Publications

Development of a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor (MK-8245) to Establish a Therapeutic Window for the Treatment of Diabetes and Dyslipidemia

Renata M. Oballa, Liette Belair, W. Cameron Black et al. · Journal of Medicinal Chemistry · 2011 · 142 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The Structural Basis for the Selectivity of Benzotriazole Inhibitors of PTP1B

Giovanna Scapin, Sangita B. Patel, Joseph W. Becker et al. · Biochemistry · 2003 · 105 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets

Deena Waddleton, Weizhen Wu, Yue Feng et al. · Biochemical Pharmacology · 2008 · 72 citations

Life Sciences, Biochemistry, Endocrinology +17

Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors

Cheuk K. Lau, Christopher I. Bayly, Jacques Yves Gauthier et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

The development of potent non-peptidic PTP-1B inhibitors

Claude Dufresne, Patrick Roy, Zhaoyin Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

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