Karel Lavrijsen

A predictive model for substrates of cytochrome P450-debrisoquine (2D6)

Luc Koymans, Nico Vermeulen, S.A.B.E. van Acker et al. · Chemical Research in Toxicology · 1992 · 152 citations

Bioorganic Chemistry, Molecular Biology, Cytochrome P450-debrisoquine +21

The Metabolism and Excretion of Galantamine in Rats, Dogs, and Humans

Geert Mannens, Cor Snel, Jan Hendrickx et al. · Drug Metabolism and Disposition · 2002 · 97 citations

The pharmacokinetics of itraconazole in animals and man: an overview

J Heykants, M. Michiels, W. Meuldermans et al. · 1987 · 93 citations

Pharmacological Study, Medicine, Clinical Pharmacology +5

Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans.

Aimée Paulussen, Karel Lavrijsen, Hilde Bohets et al. · Pharmacogenetics · 2000 · 91 citations

Genetics, Human Polymorphism, Pathology +20

MEIC Evaluation of Acute Systemic Toxicity

Cecilia Clemedson, Elisabeth McFarlane-Abdulla, Marianne Andersson et al. · Alternatives to Laboratory Animals · 1996 · 82 citations

Toxicology Testing, Different Toxicity Assays, Comparative Toxicology +21