Luc Koymans

Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant <i>Candida albicans</i> Clinical Isolates Contribute to Resistance to Azole Antifungal Agents

Dominique Sanglard, Françoise Ischer, Luc Koymans et al. · Antimicrobial Agents and Chemotherapy · 1998 · 461 citations · Full text

Contribution of mutations in the cytochrome P450 14α-demethylase (Erg11p, Cyp51p) to azole resistance in Candida albicans

Patrick Marichal, Luc Koymans, Staf Willemsens et al. · Microbiology · 1999 · 370 citations

Cytochrome P450 14α-Demethylase, Molecular Biology, Amino Acid Substitutions +17

Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors

Jianping Ding, Kalyan Das, Henri Moereels et al. · Nature Structural & Molecular Biology · 1995 · 298 citations

Biochemistry, Diverse Nonnucleoside Inhibitors, Natural Sciences +10

Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant

Kalyan Das, Jianping Ding, Y. Hsiou et al. · Journal of Molecular Biology · 1996 · 187 citations

Wild-type Hiv-1 Rt, Biochemistry, 9-Cl Tibo Complexed +12

A predictive model for substrates of cytochrome P450-debrisoquine (2D6)

Luc Koymans, Nico Vermeulen, S.A.B.E. van Acker et al. · Chemical Research in Toxicology · 1992 · 152 citations

Bioorganic Chemistry, Molecular Biology, Cytochrome P450-debrisoquine +21