Amanda A. Bouffard

CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

Bryan D. Choi, Xiaoling Yu, Ana P. Castaño et al. · Nature Biotechnology · 2019 · 558 citations

Life Sciences, Immunology, Molecular Biology +16

CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours

Rebecca C. Larson, Michael C. Kann, Stefanie R. Bailey et al. · Nature · 2022 · 349 citations

Life Sciences, Immunology, Oncology +16

CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma

Bryan D. Choi, Xiaoling Yu, Ana P. Castaño et al. · Journal for ImmunoTherapy of Cancer · 2019 · 283 citations · Full text

Medicine, Immunology, Oncology +17

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

Max Jan, Irene Scarfò, Rebecca C. Larson et al. · Science Translational Medicine · 2021 · 258 citations · Full text

Medicine, Oncology, Pharmacology +17

Chimeric antigen receptor costimulation domains modulate human regulatory T cell function

Angela C. Boroughs, Rebecca C. Larson, Bryan D. Choi et al. · JCI Insight · 2019 · 141 citations · Full text

Life Sciences, Immunology, Molecular Biology +17