Angela C. Boroughs

CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

Bryan D. Choi, Xiaoling Yu, Ana P. Castaño et al. · Nature Biotechnology · 2019 · 539 citations

Immunological Memory, Autoimmune Disease, Immunology +9

Chimeric antigen receptor costimulation domains modulate human regulatory T cell function

Angela C. Boroughs, Rebecca C. Larson, Bryan D. Choi et al. · JCI Insight · 2019 · 134 citations · Full text

T-regulatory Cell, Immunology, Regulatory T Cells +19

<i>C1orf106</i> is a colitis risk gene that regulates stability of epithelial adherens junctions

Vishnu Mohanan, Toru Nakata, A. Nicole Desch et al. · Science · 2018 · 127 citations · Full text

Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma

Andrea Schmidts, Maria Ormhøj, Bryan D. Choi et al. · Blood Advances · 2019 · 107 citations · Full text

A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq

Angela C. Boroughs, Rebecca C. Larson, Nemanja D. Marjanovic et al. · Molecular Therapy · 2020 · 107 citations · Full text