Concepedia

John Soong

JS

27

Publications

2K

Citations

20

H-Index

1982

Active since

Affiliations

Imperial College London(Current)

National University Hospital

National University of Singapore

National University Health System

Princess Margaret Cancer Centre

John Soong is an author at Imperial College London specializing in medicine, cancer research, and pathology.

ORCID

Top concepts

Publications per year

1982–2022

27

Publications

27

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Hong Xu, Marco Di Antonio, Steven McKinney et al. · Nature Communications · 2017 · 573 citations · Full text

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Elaine Sanij, Katherine M. Hannan, Jiachen Xuan et al. · Nature Communications · 2020 · 213 citations · Full text

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

Amit Khot, Natalie Brajanovski, Donald P. Cameron et al. · Cancer Discovery · 2019 · 197 citations

Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies

John Hilton, Karen A. Gelmon, Philippe L. Bédard et al. · Nature Communications · 2022 · 128 citations · Full text

Quantifying the prevalence of frailty in English hospitals

John Soong, Shannon D. Scott, K Donald et al. · BMJ Open · 2015 · 120 citations · Full text

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