Kenneth D. Roth

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

Bo Tan, Debra A. Young, Zhao-Hai Lu et al. · Journal of Biological Chemistry · 2012 · 173 citations · Full text

Glycobiology, Nad+ Biosynthesis, Metabolic Remodeling +19

The Folate Pathway Inhibitor Pemetrexed Pleiotropically Enhances Effects of Cancer Immunotherapy

David Schaer, Sandaruwan Geeganage, Nelusha Amaladas et al. · Clinical Cancer Research · 2019 · 121 citations

A Picomole-Scale Method for Charge Derivatization of Peptides for Sequence Analysis by Mass Spectrometry

Zhiheng Huang, Jiang Wu, Kenneth D. Roth et al. · Analytical Chemistry · 1997 · 105 citations

Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes

Valentina Pirro, Kenneth D. Roth, Yanzhu Lin et al. · The Journal of Clinical Endocrinology & Metabolism · 2021 · 105 citations

Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells

Bo Tan, Sucai Dong, Robert L. Shepard et al. · Journal of Biological Chemistry · 2015 · 55 citations · Full text

Aldo-keto Reductase, Chemoprevention Strategy, Nad+ Biosynthesis +18