Rachel Grimshaw

Pharmacokinetic-Pharmacodynamic Relationships for the Heat Shock Protein 90 Molecular Chaperone Inhibitor 17-Allylamino, 17-Demethoxygeldanamycin in Human Ovarian Cancer Xenograft Models

Udai Banerji, Michael I. Walton, Florence I. Raynaud et al. · Clinical Cancer Research · 2005 · 164 citations · Full text

Medicine, Oncology, Pharmacology +14

Idoxifene antagonizes estradiol-dependent MCF-7 breast cancer xenograft growth through sustained induction of apoptosis.

Stephen R.D. Johnston, Irene Boeddinghaus, Sharon A. Riddler et al. · PubMed · 1999 · 58 citations

Medicine, Oncology, Pharmacology +7

The deuterium isotope effect for the α-hydroxylation of tamoxifen by rat liver microsomes accounts for the reduced genotoxicity of [D₅-ethyl]tamoxifen

Michael Jarman, Grace K. Poon, Martin Rowlands et al. · Carcinogenesis · 1995 · 54 citations

Pharmacy, Oncology, Toxicology +17

A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy.

Beatrice Seddon, Geoffrey S. Payne, Laura K. Simmons et al. · PubMed · 2003 · 47 citations · Full text

Medicine, Oncology, Pharmacokinetics +15

Validation of the fluorinated 2-nitroimidazole SR-4554 as a noninvasive hypoxia marker detected by magnetic resonance spectroscopy.

Beatrice Seddon, Ross J. Maxwell, Davina J. Honess et al. · PubMed · 2002 · 30 citations

Medicine, Oncology, Pharmacology +14