A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy. - Concepedia

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A phase I study of SR-4554 via intravenous administration for noninvasive investigation of tumor hypoxia by magnetic resonance spectroscopy in patients with malignancy.

47

Citations

40

References

2003

Year

Beatrice Seddon, Geoffrey S. Payne, Laura K. Simmons, Ruth Ruddle, Rachel Grimshaw, Siew Kiang Tan, Alison Turner, Florence I. Raynaud, Gavin Halbert, Martin O. Leach,

Abstract

SR-4554 has plasma pharmacokinetic and toxicity profiles suitable for use as a hypoxia probe. It can be detected in tumors by unlocalized MRS. Additional clinical studies are warranted.

References

	Year	Citations

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