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Publication | Open Access

Pharmacokinetic-Pharmacodynamic Relationships for the Heat Shock Protein 90 Molecular Chaperone Inhibitor 17-Allylamino, 17-Demethoxygeldanamycin in Human Ovarian Cancer Xenograft Models

DOIFull Paper Access

164

Citations

40

References

2005

Year

Udai Banerji, Michael I. Walton, Florence I. Raynaud, Rachel Grimshaw, Lloyd R. Kèlland, Melani Valenti, Ian Judson, Paul Workman
Clinical Cancer Research

Abstract

Pharmacokinetic-pharmacodynamic relationships were established for 17-AAG. This information formed the basis of a pharmacokinetic-pharmacodynamic-driven phase I trial.

References

YearCitations

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