Sean Riley

Novel Selective Allosteric and Bitopic Ligands for the S1P₃ Receptor

Euijung Jo, Barun Bhhatarai, Emanuela Repetto et al. · ACS Chemical Biology · 2012 · 59 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction

Marta Sanna, Kevin P. Vincent, Emanuela Repetto et al. · Molecular Pharmacology · 2015 · 54 citations · Full text

Medicine, Cardiology, Pharmacology +17

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Miguel Guerrero, Mariangela Urbano, Eun-Kyong Kim et al. · Journal of Medicinal Chemistry · 2019 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design, Synthesis, and <i>In Vitro</i> and <i>In Vivo</i> Evaluation of an ¹⁸F-Labeled Sphingosine 1-Phosphate Receptor 1 (S1P₁) PET Tracer

Adam J. Rosenberg, Hui Liu, Hongjun Jin et al. · Journal of Medicinal Chemistry · 2016 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates

Stephanie E. Barrett, Rob S. Burke, Marc Abrams et al. · Journal of Controlled Release · 2014 · 31 citations

Pharmacy, Pharmaceutics, Pharmacology +16