Microwave-assisted extraction of coumarin and related compounds from Melilotus officinalis (L.) Pallas as an alternative to Soxhlet and ultrasound-assisted extraction

Emanuela Martino, Ilaria Ramaiola, Mariangela Urbano, +2

Journal of Chromatography A

MedicineMelilotus OfficinalisBioanalysisMicrowave-assisted ExtractionUltrasound-assisted Extraction +2

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Miguel Guerrero, Mariangela Urbano, Eun-Kyong Kim, +11

Journal of Medicinal Chemistry

Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells

Daniela Rossi, Alice Pedrali, Mariangela Urbano, +13

Bioorganic & Medicinal Chemistry

Molecular PharmacologyPc12 CellsSignal TransductionSignaling PathwayG Protein-coupled Receptor +7

Discovery, synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chemotype

Mariangela Urbano, Miguel Guerrero, Subash Velaparthi, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryThiazolidin-4-one ChemotypeDrug TargetBiochemistryNatural Sciences +7

Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists

Miguel Guerrero, Mariangela Urbano, Subash Velaparthi, +5

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicineReceptor AntagonistsReceptor (Biochemistry)Pharmacology +3

Design, synthesis, and SAR analysis of novel selective σ1 ligands

Simona Collina, Guya Loddo, Mariangela Urbano, +9

Bioorganic & Medicinal Chemistry

Pharmaceutical ChemistryNatural SciencesMedicineSar AnalysisChemistry +4

Design, synthesis and SAR analysis of novel selective σ1 ligands (Part 2)

Daniela Rossi, Mariangela Urbano, Alice Pedrali, +10

Bioorganic & Medicinal Chemistry

Pharmaceutical ChemistryPart 2Natural SciencesSar AnalysisMedicine +5

SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor

Mariangela Urbano, Miguel Guerrero, Jian Zhao, +5

Bioorganic & Medicinal Chemistry Letters

BiochemistryG Protein-coupled ReceptorNatural SciencesMedicineSar Analysis +6

Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists

Miguel Guerrero, Mariangela Urbano, Jian Zhao, +7

Bioorganic & Medicinal Chemistry Letters

BiochemistryFunctional SelectivityMedicineG Protein-coupled ReceptorReceptor (Biochemistry) +6

Discovery, design and synthesis of a selective S1P3 receptor allosteric agonist

Miguel Guerrero, Ramulu Poddutoori, Mariangela Urbano, +8

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyDrug TargetBiochemistryFunctional SelectivityMedicine +5