Christopher G. F. Cooper

SCD1 Inhibition Causes Cancer Cell Death by Depleting Mono-Unsaturated Fatty Acids

Paul Mason, Beirong Liang, Lingyun Li et al. · PLoS ONE · 2012 · 166 citations · Full text

Pathology, Cell Death, Reference Scd1 Inhibitors +16

Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease

Karen M. Ashe, Dinesh S. Bangari, Lingyun Li et al. · PLoS ONE · 2011 · 72 citations · Full text

Sandhoff Disease, Glycobiology, Immunology +17

Iminosugar-based inhibitors of glucosylceramide synthase prolong survival but paradoxically increase brain glucosylceramide levels in Niemann–Pick C mice

Jennifer B. Nietupski, Joshua Pacheco, Wei‐Lien Chuang et al. · Molecular Genetics and Metabolism · 2012 · 61 citations

Molecular Pharmacology, Biochemistry, Medicine +11

A Non-Covalent Strategy for the Assembly of Supramolecular Photocurrent-Generating Systems

Ernesto Soto, John C. MacDonald, Christopher G. F. Cooper et al. · Journal of the American Chemical Society · 2003 · 50 citations

Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease

Karen M. Ashe, Kristin M. Taylor, Qiuming Chu et al. · Molecular Genetics and Metabolism · 2010 · 46 citations

Pompe Disease, Glycogen Biosynthesis, Biochemistry +4