Karen M. Ashe - Concepedia

Author

Karen M. Ashe

Icahn School of Medicine at Mount Sinai

Also Known As

Karen Ashe, Karen M Ashe, Karen M. Ashe

Publications

475

Citations

H-Index

Concepts

All Affiliations

Icahn School of Medicine at Mount Sinai Amsterdam UMC Location University of Amsterdam University of Amsterdam

About

Karen M. Ashe is an author at Icahn School of Medicine at Mount Sinai specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	345
2	Biochemistry	5	5	350
3	Natural Sciences	2	2	171
4	Biomolecular Engineering	1	1	72
5	Cell Biology	1	1	72

Karen M. Ashe

Publications

474

Citations

H-Index

Page 1

	Year	Citations
Efficacy of Enzyme and Substrate Reduction Therapy with a Novel Antagonist of Glucosylceramide Synthase for Fabry Disease Karen M. Ashe, Eva Budman, Dinesh S. Bangari, Molecular Medicine GlycobiologyImmunologyBiological TherapySubstrate Reduction TherapyEnzyme Replacement	2015	99
Substrate Reduction Augments the Efficacy of Enzyme Therapy in a Mouse Model of Fabry Disease John Marshall, Karen M. Ashe, Dinesh S. Bangari, PLoS ONE Enzyme TherapyGlycobiologySubstrate Reduction TherapyCarbohydrate-protein InteractionSubstrate Reduction	2010	72
Iminosugar-Based Inhibitors of Glucosylceramide Synthase Increase Brain Glycosphingolipids and Survival in a Mouse Model of Sandhoff Disease Karen M. Ashe, Dinesh S. Bangari, Lingyun Li, PLoS ONE Sandhoff DiseaseGlycobiologyImmunologyPathologyNeuropathic Glycosphingolipidoses	2011	72
Iminosugar-based inhibitors of glucosylceramide synthase prolong survival but paradoxically increase brain glucosylceramide levels in Niemann–Pick C mice Jennifer B. Nietupski, Joshua Pacheco, Wei‐Lien Chuang, Molecular Genetics and Metabolism Molecular PharmacologyBiochemistryMedicineExperimental TherapeuticNeuropharmacology	2012	61
Systemic Administration of AAV8-α-galactosidase A Induces Humoral Tolerance in Nonhuman Primates Despite Low Hepatic Expression Jennifer B. Nietupski, Gregory D Hurlbut, Robin J. Ziegler, Molecular Therapy	2011	54
Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease Karen M. Ashe, Kristin M. Taylor, Qiuming Chu, Molecular Genetics and Metabolism Pompe DiseaseGlycogen BiosynthesisBiochemistryMtorc1 SuppressionBiochemical Genetics	2010	46
α-Galactosidase A Knockout Mice Dinesh S. Bangari, Karen M. Ashe, Robert J. Desnick, American Journal Of Pathology Knockout MouseMedicineGlycobiologyKnockout MiceCellular Biochemistry	2014	41
Merits of Combination Cortical, Subcortical, and Cerebellar Injections for the Treatment of Niemann-Pick Disease Type A Jie Bu, Karen M. Ashe, John R. Bringas, Molecular Therapy	2012	29

Page 1