Dominique Potin

New chiral auxiliaries: their use in the asymmetric hydrogenation of .beta.-acetamidocrotonates

Dominique Potin, Françoise Dumas, Jean d’Angelo · Journal of the American Chemical Society · 1990 · 68 citations

Molecular Sciences, Engineering, Chemical Measurement +13

Asymmetric Protonation of Enolates

Dominique Potin, Kevin M. Williams, J. Rebek · Angewandte Chemie International Edition in English · 1990 · 55 citations

Asymmetric Protonation, Lactam 1, Acidic Nh Group +10

Discovery and Development of 5-[(5<i>S</i>,9<i>R</i>)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101)A Small Molecule Antagonist of Leukocyte Function Associated Antigen-1

Dominique Potin, Michèle Launay, Francoise Monatlik et al. · Journal of Medicinal Chemistry · 2006 · 51 citations · Full text

Small Molecule Antagonist of Leukocyte Function Associated Antigen-1 (LFA-1): Structure−Activity Relationships Leading to the Identification of 6-((5<i>S</i>,9<i>R</i>)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic Acid (BMS-688521)

Scott H. Watterson, Zili Xiao, Dharmpal S. Dodd et al. · Journal of Medicinal Chemistry · 2010 · 43 citations · Full text

Discovery of Selective and Orally Bioavailable Protein Kinase Cθ (PKCθ) Inhibitors from a Fragment Hit

Dawn M. George, Eric C. Breinlinger, Michael Friedman et al. · Journal of Medicinal Chemistry · 2014 · 42 citations · Full text

Drug Target, Immunology, Pharmacotherapy +19