Philippe Levêque

Antibody‐functionalized nanoparticles for imaging cancer: influence of conjugation to gold nanoparticles on the biodistribution of ⁸⁹Zr‐labeled cetuximab in mice

Linda Karmani, Daniel Labar, Vanessa Valembois et al. · Contrast Media & Molecular Imaging · 2013 · 89 citations · Full text

Pharmacy, Nuclear Medicine, Pharmaceutics +17

Hsp90 Is Cleaved by Reactive Oxygen Species at a Highly Conserved N-Terminal Amino Acid Motif

Raphaël Beck, Nicolas Dejeans, Christophe Glorieux et al. · PLoS ONE · 2012 · 68 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study

Raphaël Beck, Rozangela Curi Pedrosa, Nicolas Dejeans et al. · Investigational New Drugs · 2010 · 66 citations

Life Sciences, Cancer Biology, Oncology +16

Determination of tumour hypoxia with [18F]EF3 in patients with head and neck tumours: a phase I study to assess the tracer pharmacokinetics, biodistribution and metabolism

Pierre Mahy, Xavier Geets, Max Lonneux et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2008 · 37 citations

Medicine, Oncology, Pharmacokinetics +13

Preclinical validation of the hypoxia tracer 2-(2-nitroimidazol-1-yl)-N-(3,3,3-[18F]trifluoropropyl)acetamide, [18F]EF3

Pierre Mahy, Marc De Bast, Philippe Levêque et al. · European Journal of Nuclear Medicine and Molecular Imaging · 2004 · 34 citations

Medicine, Pharmacology, Molecular Pharmacology +5