T. F. MICH

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay

John M. Domagala, Lori Doyle Hanna, Carl L. Heifetz et al. · Journal of Medicinal Chemistry · 1986 · 265 citations

Life Sciences, Biochemistry, Medicinal Chemistry +9

1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure activity relationships at N1 for the quinolone antibacterials

John M. Domagala, Carl L. Heifetz, Marland P. Hutt et al. · Journal of Medicinal Chemistry · 1988 · 96 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

7-Substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials

John M. Domagala, Susan E. Hagen, Carl L. Heifetz et al. · Journal of Medicinal Chemistry · 1988 · 36 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13

1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid. New quinolone antibacterial with potent gram-positive activity

John M. Domagala, Carl L. Heifetz, T. F. MICH et al. · Journal of Medicinal Chemistry · 1986 · 35 citations

Medicine, Chemistry, Pharmacology +5

The generation of benzyne - A warning

T. F. MICH, Everett J. Nienhouse, Thomas E. Farino et al. · Journal of Chemical Education · 1968 · 34 citations

Natural Sciences, Chemistry, Analytical Chemistry +7