Marland P. Hutt

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay

John M. Domagala, Lori Doyle Hanna, Carl L. Heifetz et al. · Journal of Medicinal Chemistry · 1986 · 265 citations

Life Sciences, Biochemistry, Medicinal Chemistry +9

Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids

Joseph P. Sanchez, John M. Domagala, Susan E. Hagen et al. · Journal of Medicinal Chemistry · 1988 · 136 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

1-Substituted 7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. New quantitative structure activity relationships at N1 for the quinolone antibacterials

John M. Domagala, Carl L. Heifetz, Marland P. Hutt et al. · Journal of Medicinal Chemistry · 1988 · 96 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

2‐Phenyl‐5‐(trichloromethyl)‐1,3,4‐oxadiazoles, A new class of antimalarial substances

Marland P. Hutt, Edward F. Elslager, Leslie M. Werbel · Journal of Heterocyclic Chemistry · 1970 · 39 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

7-Substituted 5-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids: synthesis and biological activity of a new class of quinolone antibacterials

John M. Domagala, Susan E. Hagen, Carl L. Heifetz et al. · Journal of Medicinal Chemistry · 1988 · 36 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13