Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

Min Xiu, Juanjuan Xing, Shaoqing Yu, +2

Cellular Physiology and Biochemistry

Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90

Purva Bali, Michael Pranpat, James E. Bradner, +9

Journal of Biological Chemistry

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3

Prince George, Purva Bali, Srinivas Annavarapu, +8

Blood

Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B.

Lianne Fuino, Purva Bali, Sylvie Wittmann, +6

PubMed

Histone ModificationsBreast OncologyCancer BiologyEpigeneticsTumor Biology +15

Abrogation of Heat Shock Protein 70 Induction as a Strategy to Increase Antileukemia Activity of Heat Shock Protein 90 Inhibitor 17-Allylamino-Demethoxy Geldanamycin

Fei Guo, Kathy Rocha, Purva Bali, +9

Cancer Research

ApoptosisImmunologyCell DeathIncrease Antileukemia ActivityPharmaceutical Chemistry +16

Cancer-associated fibroblasts promote the progression of endometrial cancer via the SDF-1/CXCR4 axis

Fei Teng, Wenyan Tian, Yingmei Wang, +5

Journal of Hematology & Oncology

Cotreatment with Histone Deacetylase Inhibitor LAQ824 Enhances Apo-2L/Tumor Necrosis Factor-Related Apoptosis Inducing Ligand-Induced Death Inducing Signaling Complex Activity and Apoptosis of Human Acute Leukemia Cells

Fei Guo, Celia Sigua, Jianguo Tao, +7

Cancer Research

Cinnamic Acid HydroxamateHematological MalignancyCell SignalingMedicineApoptosis +10

miR-210 activates notch signaling pathway in angiogenesis induced by cerebral ischemia

Yuanlei Lou, Fei Guo, Fen Liu, +7

Molecular and Cellular Biochemistry

Cerebral IschemiaDevelopmental BiologyAngiogenesisMir-210 ActivatesMicrovascular Dysfunction +10

Mechanistic role of heat shock protein 70 in Bcr-Abl–mediated resistance to apoptosis in human acute leukemia cells

Fei Guo, Celia Sigua, Purva Bali, +10

Blood

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative–(BMS 247550) and Apo-2L/TRAIL–induced apoptosis

Fei Guo, Ramadevi Nimmanapalli, Shanthi R. Paranawithana, +7

Blood