Alfredo G. Tomasselli

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck et al. · Nature · 1999 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +14

Structure at 2.5-.ANG. resolution of chemically synthesized Human Immunodeficiency Virus Type 1 protease complexed with a hydroxyethylene-based inhibitor

Mariusz Jaskólski, Alfredo G. Tomasselli, Tomi K. Sawyer et al. · Biochemistry · 1991 · 229 citations

Life Sciences, Biochemistry, Biology +10

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Jill Chrencik, Akshay Patny, Iris Leung et al. · Journal of Molecular Biology · 2010 · 226 citations

Life Sciences, Biochemistry, Molecular Biology +14

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

William Watt, Kenneth A. Koeplinger, Ana M. Mildner et al. · Structure · 1999 · 182 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Prediction of the tertiary structure of a caspase‐9/inhibitor complex

Kuo‐Chen Chou, Alfredo G. Tomasselli, Robert L. Heinrikson · FEBS Letters · 2000 · 143 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13