Alfredo G. Tomasselli

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck et al. · Nature · 1999 · 1.4K citations

Alzheimer's Disease, Biochemistry, Proteasome +3

Structure at 2.5-.ANG. resolution of chemically synthesized Human Immunodeficiency Virus Type 1 protease complexed with a hydroxyethylene-based inhibitor

Mariusz Jaskólski, Alfredo G. Tomasselli, Tomi K. Sawyer et al. · Biochemistry · 1991 · 229 citations

Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

Jill Chrencik, Akshay Patny, Iris Leung et al. · Journal of Molecular Biology · 2010 · 224 citations

Protein Function, Signal Transduction, Biochemistry +13

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

William Watt, Kenneth A. Koeplinger, Ana M. Mildner et al. · Structure · 1999 · 180 citations · Full text

Atomic-resolution Structure, Human Caspase-8, Protein Function +15

Prediction of the tertiary structure of a caspase‐9/inhibitor complex

Kuo‐Chen Chou, Alfredo G. Tomasselli, Robert L. Heinrikson · FEBS Letters · 2000 · 142 citations · Full text