Alfredo G. Tomasselli

Author

Also Known As

A. G. TOMASSELLI, A. Tomasselli, A.G. Tomasselli, ALFREDO G. TOMASSELLI, Alfredo G Tomasselli, Alfredo G. TOMASSELLI, Alfredo G. Tomasselli, Alfredo Tomasselli, Alfredo G. Tomasselli

Publications

4.9K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)W.E. Upjohn Institute for Employment Research Dartmouth College University of Freiburg Institute of Molecular and Cell Biology

About

Alfredo G. Tomasselli is an author at Pfizer (United States) specializing in medicine, natural sciences, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	18	25	2.8K
2	Natural Sciences	17	20	1.2K
3	Biochemistry	15	19	2.5K
4	Biomolecular Engineering	3	3	48
5	Engineering	2	2	38

Alfredo G. Tomasselli

Publications

4.6K

Citations

H-Index

Page 1

	Year	Citations
Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck, Nature Alzheimer's DiseaseBiochemistryProteasomeProtein MisfoldingMembrane-anchored Aspartyl Protease	1999	1.4K
Structure at 2.5-.ANG. resolution of chemically synthesized Human Immunodeficiency Virus Type 1 protease complexed with a hydroxyethylene-based inhibitor Mariusz Jaskólski, Alfredo G. Tomasselli, Tomi K. Sawyer, Biochemistry	1991	229
Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6 Jill Chrencik, Akshay Patny, Iris Leung, Journal of Molecular Biology Protein FunctionSignal TransductionBiochemistryBiomolecular Structure PredictionProtein Folding	2010	224
The atomic-resolution structure of human caspase-8, a key activator of apoptosis William Watt, Kenneth A. Koeplinger, Ana M. Mildner, Structure Atomic-resolution StructureHuman Caspase-8Protein FunctionSignal TransductionSignaling Pathway	1999	180
Prediction of the tertiary structure of a caspase‐9/inhibitor complex Kuo‐Chen Chou, Alfredo G. Tomasselli, Robert L. Heinrikson FEBS Letters	2000	142
Structure of the complex of yeast adenylate kinase with the inhibitor P1,P5-di(adenosine-5′-)pentaphosphate at 2.6 Å resolution Ursula Egner, Alfredo G. Tomasselli, Georg E. Schulz Journal of Molecular Biology Signal TransductionAldo-keto ReductaseBiochemistryNatural SciencesInhibitor P1	1987	131
Substrate analog inhibition and active site titration of purified recombinant HIV-1 protease Alfredo G. Tomasselli, Mary K. Olsen, John O. Hui, Biochemistry	1990	127
Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors Suvit Thaisrivongs, Keith David Watenpaugh, W. Jeffrey Howe, Journal of Medicinal Chemistry	1995	121
Structural relationships in the adenylate kinase family Georg E. Schulz, Emile Schiltz, Alfredo G. Tomasselli, European Journal of Biochemistry Protein FunctionMolecular PhysiologyEnzyme FamilyBiochemistryBiomolecular Structure Prediction	1986	121
Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human β-Secretase Michel Maillard, Roy K. Hom, Timothy E. Benson, Journal of Medicinal Chemistry	2007	110

Page 1