Jeffrey S. Taylor

Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations

Sean Johnson, Jeffrey S. Taylor, L.S. Beese · Proceedings of the National Academy of Sciences · 2003 · 285 citations · Full text

DARWIN: A program for docking flexible molecules

Jeffrey S. Taylor, Roger M. Burnett · Proteins Structure Function and Bioinformatics · 2000 · 133 citations

Biochemistry, Biomolecular Structure Prediction, Protein Folding +15

Structure of mammalian protein geranylgeranyltransferase type-I

Jeffrey S. Taylor · The EMBO Journal · 2003 · 133 citations · Full text

Protein Expression, Natural Sciences, Molecular Biology +3

3-Aminopyrrolidinone Farnesyltransferase Inhibitors:  Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency

Ian M. Bell, Steven N. Gallicchio, Marc Abrams et al. · Journal of Medicinal Chemistry · 2002 · 84 citations · Full text

Combinatorial Chemistry, Pharmaceutical Science, Pharmacotherapy +16

Dual Protein Farnesyltransferase−Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents

S. J. DESOLMS, Terrence M. Ciccarone, Suzanne C. MacTough et al. · Journal of Medicinal Chemistry · 2003 · 60 citations · Full text

Potent Dual Inhibitors, Medicinal Chemistry, Bioorganic Chemistry +14