Genome Sequence of the Plant Pathogen and Biotechnology Agent <i>Agrobacterium tumefaciens</i> C58

Brad Goodner, Gregory Hinkle, Stacie Gattung, +27

Science

EngineeringGeneticsPlant PathologyGenomicsAgrobacterium Tumefaciens +15

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Christopher B. Ford, Philana Ling Lin, Michael R. Chase, +9

Nature Genetics

GeneticsLatent InfectionGenomicsHigh Throughput SequencingMycobacterium Tuberculosis +15

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration

Soumya Raychaudhuri, Oleg Iartchouk, Kimberly Chin, +14

Nature Genetics

Ocular DiseaseMendelian DisorderOphthalmologyGenetic DisorderGenetics +6

Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

Paul Hardenbol, Fuli Yu, John W. Belmont, +26

Genome Research

TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts

Angelo L. Grauel, Beverly Nguyen, David A. Ruddy, +35

Nature Communications

Genetic Determinants of Drug Resistance in <i>Mycobacterium tuberculosis</i> and Their Diagnostic Value

Maha Farhat, Răzvan Sultana, Oleg Iartchouk, +16

American Journal of Respiratory and Critical Care Medicine

SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms

Ye Wang, Morvarid Mohseni, Angelo L. Grauel, +45

Scientific Reports

Filter-based hybridization capture of subgenomes enables resequencing and copy-number detection

Daniel S. Herman, G. Kees Hovingh, Oleg Iartchouk, +4

Nature Methods

BiologyHybridizationGeneticsNext-generation SequencingSequence Analysis +7

Short-term Low-Dose mTORC1 Inhibition in Aged Rats Counter-Regulates Age-Related Gene Changes and Blocks Age-Related Kidney Pathology

Tea Shavlakadze, Jiang Zhu, Sharon Wang, +11

The Journals of Gerontology Series A

AgingRenal PathologyImmunologyRenal InflammationRapamycin Complex 1 +15

<i>SOS1</i> mutations are rare in human malignancies: Implications for Noonan syndrome patients

Kenneth D. Swanson, Jordan M. Winter, Marcelo Reis, +17

Genes Chromosomes and Cancer

Somatic VariantSomatic Ptpn11Ns PatientsGenetic DisorderNoonan Syndrome Patients +12