Polyunsaturated fatty acid biosynthesis pathway determines ferroptosis sensitivity in gastric cancer

Ji-Yoon Lee, Miso Nam, Hye Young Son, +21

Proceedings of the National Academy of Sciences

CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

Jinho Seo, Eun‐Woo Lee, Hyerim Sung, +11

Nature Cell Biology

ChromatinLysosome-dependent DegradationNatural SciencesApoptosisAutophagy +9

Ubiquitination and degradation of the FADD adaptor protein regulate death receptor-mediated apoptosis and necroptosis

Eun‐Woo Lee, Jung-Hoon Kim, Ye-Hyeon Ahn, +10

Nature Communications

Signal TransductionSignaling PathwayApoptosisImmunologyAutophagy +8

The lipoprotein-associated phospholipase A2 inhibitor Darapladib sensitises cancer cells to ferroptosis by remodelling lipid metabolism

Mihee Oh, Seo Young Jang, Ji-Yoon Lee, +21

Nature Communications

Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

Aram Ko, Ji-Young Shin, Jinho Seo, +8

JNCI Journal of the National Cancer Institute

USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability

Minhyuk Jeong, Eun‐Woo Lee, Dawon Seong, +6

Oncogene

Flipl StabilitySignal TransductionSignaling PathwayApoptosisCell Death +3

Anti-melanogenic activity of schaftoside in Rhizoma Arisaematis by increasing autophagy in B16F1 cells

Pan Soo Kim, Ji Hyun Shin, Doo Sin Jo, +13

Biochemical and Biophysical Research Communications

InflammationCell AutophagyMitophagyAnti-inflammatoryAutoimmune Disease +10

Targeting Mitochondrial Oxidative Phosphorylation Abrogated Irinotecan Resistance in NSCLC

Soohyun Lee, Jae-Seon Lee, Jinho Seo, +4

Scientific Reports

Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex

Jinho Seo, Daehyeon Seong, Young Woo Nam, +8

Cell Death and Differentiation

Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling

Hae-Kyung Lee, Eun‐Woo Lee, Jinho Seo, +7

Oncogene

Transcriptional RegulationSignal TransductionSignaling PathwayMolecular PathwayMolecular Regulation +10