Paul D. Kirchhoff

LigScore: a novel scoring function for predicting binding affinities

André Krammer, Paul D. Kirchhoff, Xiaohui Jiang et al. · Journal of Molecular Graphics and Modelling · 2004 · 379 citations

Engineering, Machine Learning, Data Science +9

Electrostatic Influence on the Kinetics of Ligand Binding to Acetylcholinesterase

Zoran Radić, Paul D. Kirchhoff, Daniel M. Quinn et al. · Journal of Biological Chemistry · 1997 · 220 citations · Full text

Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence

Huiqing Zheng, Christopher J. Colvin, Benjamin K. Johnson et al. · Nature Chemical Biology · 2016 · 171 citations

Medical Microbiology, Pulmonary Tuberculosis, Health Sciences +7

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

Weiguo Xiang, Lijie Zhao, Xin Han et al. · Journal of Medicinal Chemistry · 2021 · 134 citations · Full text

Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents

Jessica L. Bell, Andrew J. Haak, Susan M. Wade et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 68 citations · Full text

Medicinal Chemistry, Drug Targeting, Rho/mkl1/srf Transcriptional Pathway +10