Déborah Perez‐Fernandez

Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin

Tanja Matt, Chyan Leong Ng, Kathrin Lang et al. · Proceedings of the National Academy of Sciences · 2012 · 210 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

Déborah Perez‐Fernandez, Dmitri Shcherbakov, Tanja Matt et al. · Nature Communications · 2014 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Loss of osteoprotegerin expression in the inner ear causes degeneration of the cochlear nerve and sensorineural hearing loss

Shyan‐Yuan Kao, Judith S. Kempfle, Déborah Perez‐Fernandez et al. · Neurobiology of Disease · 2013 · 46 citations · Full text

Medicine, Audiology, Otolaryngology +16

Identification and Evaluation of Improved 4′-<i>O</i>-(Alkyl) 4,5-Disubstituted 2-Deoxystreptamines as Next-Generation Aminoglycoside Antibiotics

Stefan Duscha, Heithem Boukari, Dimitri Shcherbakov et al. · mBio · 2014 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis and Evaluation of Paromomycin Derivatives Modified at C(4′)

Rashmi Pathak, Déborah Perez‐Fernandez, Rahul S. Nandurdikar et al. · Helvetica Chimica Acta · 2008 · 26 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11