Stefan Duscha

Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin

Tanja Matt, Chyan Leong Ng, Kathrin Lang et al. · Proceedings of the National Academy of Sciences · 2012 · 205 citations · Full text

Hybrid Ribosomes, Antibacterial Activity, Antimicrobial Chemotherapy +17

XBP1 mitigates aminoglycoside-induced endoplasmic reticulum stress and neuronal cell death

Naoki Oishi, Stefan Duscha, Heithem Boukari et al. · Cell Death and Disease · 2015 · 77 citations · Full text

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

Déborah Perez‐Fernandez, Dmitri Shcherbakov, Tanja Matt et al. · Nature Communications · 2014 · 73 citations · Full text

Structure-Activity Relationships among the Kanamycin Aminoglycosides: Role of Ring I Hydroxyl and Amino Groups

Sumantha Salian, Tanja Matt, Rashid Akbergenov et al. · Antimicrobial Agents and Chemotherapy · 2012 · 51 citations · Full text

Medicinal Chemistry, Kanamycin Aminoglycosides, Kanamycin A +15

Ribosomal mistranslation leads to silencing of the unfolded protein response and increased mitochondrial biogenesis

Dmitri Shcherbakov, Youjin Teo, Heithem Boukari et al. · Communications Biology · 2019 · 48 citations · Full text