Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice

Tatiana Takiishi, Hannelie Korf, Tom L. Van Belle, +14

Journal of Clinical Investigation

ImmunologyImmune RegulationImmunotherapyTolerance RestorationAntigen-specific Tolerance +15

1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism

Hannelie Korf, Mathias Wenes, Benoı̂t Stijlemans, +6

Immunobiology

Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by<i>Lactococcus lactis</i>Reverses Diabetes in Recent-Onset NOD Mice

Sofie Robert, Conny Gysemans, Tatiana Takiishi, +13

Diabetes

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationInnate Immunity +21

Dietary Supplementation With High Doses of Regular Vitamin D3 Safely Reduces Diabetes Incidence in NOD Mice When Given Early and Long Term

Tatiana Takiishi, Lei Ding, Femke Baeke, +9

Diabetes

NutritionImmunologyRegular Vitamin D3Dietary SupplementationInflammation +22

Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting<i>Lactococcus lactis</i>in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells

Tatiana Takiishi, Dana P. Cook, Hannelie Korf, +11

Diabetes

Vitamin D and Diabetes

Tatiana Takiishi, Conny Gysemans, Roger Bouillon, +1

Rheumatic Disease Clinics of North America

NutritionMedicineDiabetesClinical NutritionDiabetic Kidney Disease +3

Combining MK626, a Novel DPP-4 Inhibitor, and Low-Dose Monoclonal CD3 Antibody for Stable Remission of New-Onset Diabetes in Mice

Lei Ding, Conny Gysemans, Geert Stangé, +9

PLoS ONE

Novel Dpp-4 InhibitorImmunologyImmune RegulationDurable Diabetes RemissionImmune System +18

Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes

Femke Baeke, Tina Belle, Tatiana Takiishi, +5

Diabetologia

Autoimmune DiseaseDiabetesImmunologyVitamin D AnalogueAutoimmunity +6

Short chain fatty acids (SCFAs) improves TNBS-induced colitis in zebrafish

Camila Morales, Mariana Abrantes do Amaral, Izabella Karina Xavier, +7

Current Research in Immunology

Different wild type strains of zebrafish show divergent susceptibility to TNBS-induced intestinal inflammation displaying distinct immune cell profiles

Bárbara Nunes Padovani, Mariana Abrantes do Amaral, Camila Morales, +8

Current Research in Immunology