Johannes Schulz‐Fincke

Nonpeptidic Propargylamines as Inhibitors of Lysine Specific Demethylase 1 (LSD1) with Cellular Activity

Martin Schmitt, Alexander‐Thomas Hauser, Luca Carlino et al. · Journal of Medicinal Chemistry · 2013 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML

Jessica Barth, Khalil Abou‐El‐Ardat, Denis Dalic et al. · Leukemia · 2019 · 67 citations

Medicine, Molecular Biology, Pharmacology +5

Structure-activity studies on N -Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation

Johannes Schulz‐Fincke, Mirjam Hau, Jessica Barth et al. · European Journal of Medicinal Chemistry · 2017 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

A quinone mediator drives oxidations catalysed by alcohol dehydrogenase-containing cell lysates

Julian Haas, Michael A. Schätzle, Syed Masood Husain et al. · Chemical Communications · 2016 · 18 citations

Life Sciences, Biochemistry, Molecular Biology +12

Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate

Martin Schmitt, Kathrin I. Ladwein, Luca Carlino et al. · SLAS DISCOVERY · 2014 · 11 citations · Full text

Medicine, Molecular Biology, Pharmacology +16