Nicholas E. Powers

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

Isak W. Tengesdal, Dinoop Ravindran Menon, Douglas G. Osborne et al. · Proceedings of the National Academy of Sciences · 2021 · 183 citations · Full text

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression

Isak W. Tengesdal, Alberto Dinarello, Nicholas E. Powers et al. · Frontiers in Immunology · 2021 · 121 citations · Full text

Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses

Sonia Ndeupen, Aurélie Bouteau, Christopher Herbst et al. · PLoS Pathogens · 2022 · 31 citations · Full text

PASylation of IL-1 receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis

Nicholas E. Powers, Benjamin J. Swartzwelter, Carlo Marchetti et al. · Journal of Biological Chemistry · 2020 · 28 citations · Full text

Immunology, Renal Inflammation, Immune Regulation +21

Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease

Dennis M. de Graaf, Ralph J. A. Maas, Sanne P. Smeekens et al. · Cytokine · 2020 · 24 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +11