Dennis M. de Graaf

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

Isak W. Tengesdal, Dinoop Ravindran Menon, Douglas G. Osborne et al. · Proceedings of the National Academy of Sciences · 2021 · 183 citations · Full text

NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis

Carlo Marchetti, Benjamin J. Swartzwelter, Marije I. Koenders et al. · Arthritis Research & Therapy · 2018 · 155 citations · Full text

IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease

Jesper Falkesgaard Højen, Marie Louise Vindvad Kristensen, Amy S. McKee et al. · Nature Immunology · 2019 · 78 citations · Full text

Inflammation, Cytokine, Autoimmune Disease +11

Mitochondrial damage activates the NLRP10 inflammasome

Tomasz Próchnicki, Matilde B. Vasconcelos, Kim S. Robinson et al. · Nature Immunology · 2023 · 66 citations

Inflammation, Mitochondrial Damage, Mitochondrial Function +6

Interleukin 38 alleviates aortic valve calcification by inhibition of NLRP3

Erlinda The, Dennis M. de Graaf, Yufeng Zhai et al. · Proceedings of the National Academy of Sciences · 2022 · 39 citations · Full text