Christine F. Gelin

Identification of a Novel Small Molecule HIF-1α Translation Inhibitor

Takuhito Narita, Shaoman Yin, Christine F. Gelin et al. · Clinical Cancer Research · 2009 · 119 citations · Full text

A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1<i>H</i>-[1,2,3]triazolo[4,5-<i>c</i>]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate

Christa C. Chrovian, Akinola Soyode-Johnson, Alexander A. Peterson et al. · Journal of Medicinal Chemistry · 2017 · 73 citations · Full text

4-Methyl-6,7-dihydro-4<i>H</i>-triazolo[4,5-<i>c</i>]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate

Michael A. Letavic, Brad M. Savall, Brett D. Allison et al. · Journal of Medicinal Chemistry · 2017 · 65 citations · Full text

Clinical Candidate, Pharmacotherapy, Vivo Target Engagement +16

Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J

K. C. Nicolaou, Troy Lister, Ross M. Denton et al. · Angewandte Chemie International Edition · 2007 · 45 citations

Cross-coupling Reaction, Artochamins F, Engineering +10

Synthesis of the QRSTU Domain of Maitotoxin and Its 85-<i>epi</i>- and 86-<i>epi</i>-Diastereoisomers

K. C. Nicolaou, Christine F. Gelin, Jae Hong Seo et al. · Journal of the American Chemical Society · 2010 · 40 citations · Full text