Christa C. Chrovian - Concepedia

Author

Christa C. Chrovian

Janssen (United States)ORCID

Also Known As

C. C. Chrovian, C. CHROVIAN, C. Chrovian, Christa C. Chrovian, Christa Chrovian, Chrovian, Christa C.

Publications

415

Citations

H-Index

Concepts

All Affiliations

Janssen (United States)University of Michigan

About

Christa C. Chrovian is an author at Janssen (United States) specializing in pharmacology, organic chemistry, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	132
2	Engineering	2	2	93
3	Social Sciences	1	1	75
4	Biochemistry	1	1	13
5	Biomolecular Engineering	1	1	55

Christa C. Chrovian

Publications

311

Citations

H-Index

Page 1

	Year	Citations
Neuropsychopharmacology of JNJ-55308942: evaluation of a clinical candidate targeting P2X7 ion channels in animal models of neuroinflammation and anhedonia Anindya Bhattacharya, Brian Lord, Jan-Sebastian Grigoleit, Neuropsychopharmacology NeurophysiologyMedicinePharmacologyP2x7 Ion ChannelsAnimal Models	2018	75
A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1<i>H</i>-[1,2,3]triazolo[4,5-<i>c</i>]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate Christa C. Chrovian, Akinola Soyode-Johnson, Alexander A. Peterson, Journal of Medicinal Chemistry	2017	73
Total Synthesis of Aigialomycin D: Surprising Chemoselectivity Dependence on Alkyne Structure in Nickel-Catalyzed Cyclizations Christa C. Chrovian, Beth Knapp‐Reed, John Montgomery Organic Letters Surprising Chemoselectivity DependenceChemical EngineeringEngineeringHeterocyclicTotal Synthesis	2008	55
Surprising Role of Aryl Halides in Nickel-Catalyzed Reductive Aldol Reactions Christa C. Chrovian, John Montgomery Organic Letters Cross-coupling ReactionEngineeringAryl Iodide AdditiveUnexpected RequirementInitiation Step	2007	38
Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists Dale A. Rudolph, Jesús Alcázar, Michael K. Ameriks, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryMedicinePharmacological AgentPharmacotherapyHeterocycle Chemistry	2015	32
Novel Phenyl-Substituted 5,6-Dihydro-[1,2,4]triazolo[4,3-<i>a</i>]pyrazine P2X7 Antagonists with Robust Target Engagement in Rat Brain Christa C. Chrovian, Akinola Soyode-Johnson, Hong Ao, ACS Chemical Neuroscience Robust Target EngagementMolecular PharmacologyMedicinal ChemistryPharmacological StudyMedicine	2016	25
Identification of benzofuran central cores for the inhibition of leukotriene A4 hydrolase Wendy Eccles, Jonathan M. Blevitt, Jamila N. Booker, Bioorganic & Medicinal Chemistry Letters Aldo-keto ReductaseAldehyde DehydrogenaseLeukotriene A4 HydrolaseBiochemistryOrganic Chemistry	2012	13

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