Total Synthesis of (−)-Bafilomycin A₁

Karl A. Scheidt, Thomas D. Bannister, Akihiro Tasaka, +4

Journal of the American Chemical Society

Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8

Michael P. Maher, Michael K. Ameriks, Brad M. Savall, +10

Journal of Pharmacology and Experimental Therapeutics

4-Methyl-6,7-dihydro-4<i>H</i>-triazolo[4,5-<i>c</i>]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate

Michael A. Letavic, Brad M. Savall, Brett D. Allison, +23

Journal of Medicinal Chemistry

Clinical CandidatePharmacotherapyVivo Target EngagementExperimental PharmacologyPharmaceutical Chemistry +14

Identification of a Potent, Selective, and Orally Active Leukotriene A₄ Hydrolase Inhibitor with Anti-Inflammatory Activity

Cheryl A. Grice, Kevin L. Tays, Brad M. Savall, +13

Journal of Medicinal Chemistry

Lta 4HDrug TargetImmunologyChemical BiologyPharmaceutical Chemistry +15

Total Synthesis of Formamicin

Timothy B. Durham, Nicolas Blanchard, Brad M. Savall, +2

Journal of the American Chemical Society

Synthesis, SAR, and Pharmacological Characterization of Brain Penetrant P2X7 Receptor Antagonists

Brad M. Savall, Duncan Wu, Meri De Angelis, +6

ACS Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryPharmacological CharacterizationPharmacological StudyMedicine +10

First easily reproduced solution-phase synthesis and confirmation of superconductivity in the fullerene KxC60 (Tc = 18.0 .+-. 0.1 K)

H. Hau Wang, Aravinda M. Kini, Brad M. Savall, +6

Inorganic Chemistry

Materials ScienceSuperconducting MaterialHigh-tc SuperconductivityEngineeringNovel Superconductors +11

Discovery and SAR of 6-Alkyl-2,4-diaminopyrimidines as Histamine H₄ Receptor Antagonists

Brad M. Savall, Frank Chavez, Kevin L. Tays, +6

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryAllergyBiochemistryPhase Ii +11

Superconductivity at 28.6 K in a rubidium-C60 fullerene compound, RbxC60, synthesized by a solution-phase technique

H. Hau Wang, Aravinda M. Kini, Brad M. Savall, +6

Inorganic Chemistry

Superconducting MaterialEngineeringAltmetric Attention ScoreOrganometallic ElectrochemistryOrganic Chemistry +16

Identification of (<i>R</i>)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-5(4<i>H</i>)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor

Devin M. Swanson, Brad M. Savall, Kevin J. Coe, +17

Journal of Medicinal Chemistry

Drug TargetPharmacotherapyPharmaceutical ChemistryPotent P2x7 AntagonistMolecular Pharmacology +17