Richard T. Darrington

Irreversible aggregation of recombinant bovine granulocyte-colony stimulating factor (bG-CSF) and implications for predicting protein shelf life

Christopher J. Roberts, Richard T. Darrington, Maureen B. Whitley · Journal of Pharmaceutical Sciences · 2003 · 87 citations · Full text

Life Sciences, Biochemistry, Immunology +12

Evidence for a Common Intermediate in Insulin Deamidation and Covalent Dimer Formation: Effects of pH and Aniline Trapping in Dilute Acidic Solutions

Richard T. Darrington, Bradley D. Anderson · Journal of Pharmaceutical Sciences · 1995 · 60 citations

Life Sciences, Biochemistry, Molecular Biology +13

Preformulation studies oriented toward sustained delivery of recombinant somatotropins

Michael J. Hageman, Juliane M. Bauer, Peggy L. Possert et al. · Journal of Agricultural and Food Chemistry · 1992 · 55 citations

Pharmacy, Food Science, Pharmaceutics +5

The Role of Intramolecular Nucleophilic Catalysis and the Effects of Self-Association on the Deamidation of Human Insulin at Low pH

Richard T. Darrington, Bradley D. Anderson · Pharmaceutical Research · 1994 · 40 citations

Life Sciences, Biochemistry, Chemistry +16

Effects of Insulin Concentration and Self-Association on the Partitioning of Its A-21 Cyclic Anhydride Intermediate to Desamido Insulin and Covalent Dimer

Richard T. Darrington, Bradley D. Anderson · Pharmaceutical Research · 1995 · 31 citations

Life Sciences, Biochemistry, Endocrinology +10