Hannah F. Sore

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates

Stephen J. Walsh, Soleilmane Omarjee, Warren R. J. D. Galloway et al. · Chemical Science · 2018 · 125 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17

Specific inhibition of CK2α from an anchor outside the active site

P. Brear, Claudia De Fusco, Kathy Hadje Georgiou et al. · Chemical Science · 2016 · 73 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066

Claudia De Fusco, P. Brear, Jessica Iegre et al. · Bioorganic & Medicinal Chemistry · 2017 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Partially Saturated Bicyclic Heteroaromatics as an sp³‐Enriched Fragment Collection

David G. Twigg, Noriyasu Kondo, Sophie L. Mitchell et al. · Angewandte Chemie International Edition · 2016 · 61 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Diversity-Oriented Synthesis of Macrocycle Libraries for Drug Discovery and Chemical Biology

David R. Spring, Súil Collins, Sean Bartlett et al. · Synthesis · 2016 · 53 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +17