Tumor‐associated macrophages exhibit pro‐ and anti‐inflammatory properties by which they impact on pancreatic tumorigenesis

Ole Helm, Janka Held‐Feindt, Evelin Grage‐Griebenow, +10

International Journal of Cancer

ImmunologyImmunoeditingPathologyImmunotherapeuticsCancer Biology +20

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

Sascha Rahn, Vivien Zimmermann, Fabrice Viol, +9

Cancer Letters

Stem Cell PropertiesPancreatic CancerDiabetesPathologyRisk Factor +5

CD4⁺T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4⁺T cells in pancreatic cancer development

Lisa Goebel, Evelin Grage‐Griebenow, Artur Gorys, +10

OncoImmunology

Comparative Characterization of Stroma Cells and Ductal Epithelium in Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma

Ole Helm, Ruben Mennrich, Domantas Petrick, +11

PLoS ONE

Vimentin ExpressionT-regulatory CellImmunologyGastroenterologyPathology +20

Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia

Kirsten Hattermann, Susanne Sebens, Ole Helm, +4

Oncology Reports

The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells

Sarah Arfmann-Knübel, Birte Struck, Geeske Genrich, +4

PLoS ONE

PathologyCancer BiologyCellular PhysiologyTumor BiologyEpithelial-mesenchymal Transition +18

Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

K. Diehl, L-A Dinges, Ole Helm, +6

Oncogene

Colonic Epithelial CellsCarrier ExpressionGastrointestinal OncologyMedicinePathology +5

Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling

Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, +7

Oncotarget

M1 and M2: there is no “good” and “bad”—How macrophages promote malignancy-associated features in tumorigenesis

Ole Helm, Janka Held‐Feindt, H. Schäfer, +1

OncoImmunology

Tumor-associated MacrophagesImmunologyPathologyCancer BiologyTumor Biology +16

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma

Lennart Lenk, Maren Pein, Olga Will, +16

OncoImmunology

ImmunologyBiological MicroenvironmentsPathologyCancer BiologyTumor Biology +17