Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

Sascha Rahn, Vivien Zimmermann, Fabrice Viol, +9

Cancer Letters

Stem Cell PropertiesPancreatic CancerDiabetesPathologyRisk Factor +5

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma

Lennart Lenk, Maren Pein, Olga Will, +16

OncoImmunology

ImmunologyBiological MicroenvironmentsPathologyCancer BiologyTumor Biology +17

Metastasis of pancreatic cancer: An uninflamed liver micromilieu controls cell growth and cancer stem cell properties by oxidative phosphorylation in pancreatic ductal epithelial cells

Alexander Fabian, Simon Henry Stegner, Lauritz Miarka, +15

Cancer Letters

OncologyPancreatic CancerMedicineLiver PhysiologyPathology +7

Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas

Christoph Fraune, Ronald Simon, Claudia Hube‐Magg, +16

Endocrine Pathology

Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

Hendrike Knaack, Lennart Lenk, Lisa-Marie Philipp, +12

Oncotarget

Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors

Angela M. Carter, Nilesh Kumar, Brendon Herring, +20

Oncogenesis

Cancer BiologyTumor BiologyActive Cdk5Pancreatic CancerCancer Cell Biology +14

Cancer-Associated Fibroblasts Induce Proliferation and Therapeutic Resistance to Everolimus in Neuroendocrine Tumors through STAT3 Activation

Tania Amin, Fabrice Viol, Jenny Krause, +12

Neuroendocrinology

Targeting HDACs in Pancreatic Neuroendocrine Tumor Models

R. Schmitz, Jan Kleilein, Jessica L. Bell, +9

Cells

Hdac InhibitionPancreatic CancerEpigenetic RegulationMedicineEpigenomics +9

Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy

Fabrice Viol, Bence Sipos, Martina Fahl, +8

Cellular Oncology

High Serum Levels of Wnt Signaling Antagonist Dickkopf-Related Protein 1 Are Associated with Impaired Overall Survival and Recurrence in Esophageal Cancer Patients

José Giron Ramirez, Daniel J. Smit, Fabrice Viol, +5

Cancers