Young Don Kwak

The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number

Alfonso Lavado, Jun Yong Park, Joshua Paré et al. · Developmental Cell · 2018 · 122 citations · Full text

Medicine, Genetics, Molecular Genetics +11

Statin's Excitoprotection Is Mediated by sAPP and the Subsequent Attenuation of Calpain-Induced Truncation Events, Likely via Rho-ROCK Signaling

Tao Ma, YongBo Zhao, Young Don Kwak et al. · Journal of Neuroscience · 2009 · 47 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

Aditi Aditi, Susanna M. Downing, Patrick Schreiner et al. · Neuron · 2021 · 41 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage–induced neurodegeneration

Young Don Kwak, Timothy I. Shaw, Susanna M. Downing et al. · Science Advances · 2021 · 31 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors

Lavinia C. Dumitrache, Mikio Shimada, Susanna M. Downing et al. · Proceedings of the National Academy of Sciences · 2018 · 30 citations · Full text

Life Sciences, Genetics, Neuroscience +13