Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, +13

Cell

InflammationCytokineAllergySars-cov-2 InfectionCytokine Shock Syndromes +11

The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species

Alexie Papanicolaou, Marc F. Schetelig, Peter Arensburger, +60

Genome biology

MyD88/CD40 signaling retains CAR T cells in a less differentiated state

Brooke Prinzing, Patrick Schreiner, Matthew Bell, +3

JCI Insight

Vaccination versus infection with SARS‐CoV‐2: Establishment of a high avidity IgG response versus incomplete avidity maturation

Friedhelm Struck, Patrick Schreiner, Eva Staschik, +5

Journal of Medical Virology

VaccinationVaccine DevelopmentIncomplete Avidity MaturationVaccine TargetImmunodeficiencies +13

PROSER1 mediates TET2 O-GlcNAcylation to regulate DNA demethylation on UTX-dependent enhancers and CpG islands

Xiaokang Wang, Wojciech Rosikiewicz, Yurii Sedkov, +8

Life Science Alliance

Epigenetic ChangeGeneticsDna MethylationGenomic MechanismMolecular Biology +14

Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.

Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, +12

PubMed

The challenge of avidity determination in SARS‐CoV‐2 serology

Georg Bauer, Friedhelm Struck, Patrick Schreiner, +3

Journal of Medical Virology

VaccinationAvidity DeterminationViral EvolutionViral PathogenesisImmunology +10

Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

Aditi Aditi, Susanna M. Downing, Patrick Schreiner, +5

Neuron

Genome InstabilityGenetic DisorderGeneticsGenomic MechanismMolecular Genetics +3

Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail

Brandon R. Lowe, Rajesh Kumar Yadav, Ryan A. Henry, +10

eLife

GeneticsCancer-associated MutationsGliomaEpigeneticsCancer Genomes +15

Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, +13