Concepedia

Susanna M. Downing

SM

8

Publications

494

Citations

8

H-Index

2012

Active since

Affiliations

St. Jude Children's Research Hospital(Current)

German Cancer Research Center

Boston Children's Hospital

National Center for Tumor Diseases

Howard Hughes Medical Institute

Susanna M. Downing is an author at St. Jude Children's Research Hospital specializing in genetics, medicine, and genome instability.

ORCID

Top concepts

Publications per year

2012–2021

8

Publications

8

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

Sachin Katyal, Youngsoo Lee, Karin C. Nitiss et al. · Nature Neuroscience · 2014 · 145 citations · Full text

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DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis

Vanessa Enriquez‐Rios, Lavinia C. Dumitrache, Susanna M. Downing et al. · Journal of Neuroscience · 2016 · 95 citations · Full text

Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

Manasi Ratnaparkhe, John Wong, Pei‐Chi Wei et al. · Nature Communications · 2018 · 87 citations · Full text

Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors

Youngsoo Lee, Sachin Katyal, Susanna M. Downing et al. · Nature Neuroscience · 2012 · 61 citations · Full text

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Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair

Aditi Aditi, Susanna M. Downing, Patrick Schreiner et al. · Neuron · 2021 · 37 citations · Full text

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