John O. Trent

Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound

Daekyu Sun, Brian Thompson, Brian E. Cathers et al. · Journal of Medicinal Chemistry · 1997 · 784 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +11

G‐Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy

Rafael del Villar‐Guerra, John O. Trent, Jonathan B. Chaires · Angewandte Chemie International Edition · 2017 · 554 citations

Life Sciences, Biochemistry, Molecular Biology +17

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

Brian F. Clem, Sucheta Telang, Amy Clem et al. · Molecular Cancer Therapeutics · 2008 · 435 citations

Life Sciences, Oncology, Pharmacology +17

Antiproliferative Activity of G-rich Oligonucleotides Correlates with Protein Binding

Paula J. Bates, J B Kahlon, Shelia D. Thomas et al. · Journal of Biological Chemistry · 1999 · 400 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer

Brian F. Clem, Julie O’Neal, Gilles Tapolsky et al. · Molecular Cancer Therapeutics · 2013 · 277 citations · Full text

Medicine, Oncology, Pharmacology +17