Concepedia

Brian F. Clem

BF

36

Publications

3.3K

Citations

26

H-Index

2004

Active since

Affiliations

University of Louisville(Current)

James Graham Brown Foundation

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Target (United States)

Brian F. Clem is an author at University of Louisville specializing in medicine, cell biology, and tumor biology.

ORCID

Top concepts

Publications per year

2004–2023

36

Publications

36

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth

Brian F. Clem, Sucheta Telang, Amy Clem et al. · Molecular Cancer Therapeutics · 2008 · 430 citations

, , +22

Targeting aspartate aminotransferase in breast cancer

Joshua Marshall Thornburg, Kristin K. Nelson, Brian F. Clem et al. · Breast Cancer Research · 2008 · 287 citations · Full text

Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer

Brian F. Clem, Julie O’Neal, Gilles Tapolsky et al. · Molecular Cancer Therapeutics · 2013 · 272 citations · Full text

, , +13

Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases

Abdullah Yalçın, Brian F. Clem, Alan J. Simmons et al. · Journal of Biological Chemistry · 2009 · 237 citations · Full text

Lactate supports a metabolic-epigenetic link in macrophage polarization

Jordan T. Noe, Beatriz E. Rendon, Anne E. Geller et al. · Science Advances · 2021 · 221 citations · Full text

Rows per page

1–5 of 36