Ewa S. Pilka

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +13

Pathogenic bacteria attach to human fibronectin through a tandem β-zipper

Ulrich Schwarz‐Linek, Jörn M. Werner, Andrew R. Pickford et al. · Nature · 2003 · 362 citations

Life Sciences, Microbiology, Molecular Biology +16

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

Stanley S. Ng, K.L. Kavanagh, M.A. McDonough et al. · Nature · 2007 · 324 citations

Life Sciences, Genetics, Molecular Biology +15

Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity

Andrew A. Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic et al. · Cancer Discovery · 2023 · 115 citations

Medicine, Immunology, Oncology +17

Structural Snapshots for the Conformation-dependent Catalysis by Human Medium-chain Acyl-coenzyme A Synthetase ACSM2A

Grazyna Kochan, Ewa S. Pilka, F. von Delft et al. · Journal of Molecular Biology · 2009 · 113 citations

Life Sciences, Biochemistry, Molecular Biology +14