Yaara Ofir-Rosenfeld

Mdm2 Regulates p53 mRNA Translation through Inhibitory Interactions with Ribosomal Protein L26

Yaara Ofir-Rosenfeld, Kristy Boggs, Dan Michael et al. · Molecular Cell · 2008 · 234 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +12

Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity

Andrew A. Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic et al. · Cancer Discovery · 2023 · 115 citations

Medicine, Immunology, Oncology +17

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1

Yael Aylon, Yaara Ofir-Rosenfeld, Norikazu Yabuta et al. · Genes & Development · 2010 · 103 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

Anand D. Jeyasekharan, Yang Liu, Hiroyoshi Hattori et al. · Nature Structural & Molecular Biology · 2013 · 100 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Phase 1 dose escalation and cohort expansion study evaluating safety, PK, PD and clinical activity of STC-15, a METTL-3 inhibitor, in patients with advanced malignancies.

Justin C. Moser, Kyriakos P. Papadopoulos, Yaara Ofir-Rosenfeld et al. · Journal of Clinical Oncology · 2024 · 39 citations

Medicine, Oncology, Pharmacology +17