Targetable Kinase-Activating Lesions in Ph-like Acute Lymphoblastic Leukemia

Kathryn G. Roberts, Yongjin Li, Debbie Payne-Turner, +71

New England Journal of Medicine

Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

Xiang Chen, Armita Bahrami, Alberto S. Pappo, +28

Cell Reports

The genomic landscape of hypodiploid acute lymphoblastic leukemia

Linda Holmfeldt, Lei Wei, Ernesto Díaz-Flores, +60

Nature Genetics

Hematological MalignancyGenomic LandscapeMixed-phenotype Acute LeukemiaGeneticsHematology +3

C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma

Matthew Parker, Kumarasamypet M. Mohankumar, Chandanamali Punchihewa, +46

Nature

MedicineImmunologyC11orf95–rela FusionsCancer GeneticsCancer Biology +2

The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemias

Anna Andersson, Jing Ma, Jianmin Wang, +47

Nature Genetics

Hematological MalignancySomatic VariantSomatic MutationsGeneticsHematology +2

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

Robert Huether, Li Dong, Xiang Chen, +36

Nature Communications

ChromatinSomatic VariantSomatic MutationsMedicineGenetics +9

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology

Ibrahim Qaddoumi, Wilda Orisme, Ji Wen, +37

Acta Neuropathologica

Neuro-oncologySomatic VariantCancer PathologyTumor HeterogeneityPathology +7

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

Jinghui Zhang, Kelly McCastlain, Hiroki Yoshihara, +73

Nature Genetics

Hematological MalignancyMixed-phenotype Acute LeukemiaHematologyAcute Lymphoblastic LeukemiaMedicine +2

Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

Xiang Chen, Elizabeth Stewart, Anang A. Shelat, +43

Cancer Cell

Reductive StressReactive Oxygen SpecieMedicineCell BiologyRedox Biology +1

The genomic landscape of core-binding factor acute myeloid leukemias

Zachary Faber, Xiang Chen, Amanda Larson Gedman, +46

Nature Genetics

Hematological MalignancyChromatinFunctional GenomicsGenomic LandscapeMixed-phenotype Acute Leukemia +4