Kenichi Washizuka

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Fumiyuki Shirai, Takeshi Tsumura, Yoko Yashiroda et al. · Journal of Medicinal Chemistry · 2019 · 57 citations · Full text

Cancer Biology, Pharmaceutical Chemistry, Tumor Biology +17

Palladium-Catalyzed Double and Single Carbonylations of <i>β</i>-Amino Alcohols. Selective Synthesis of Morpholine-2,3-diones and Oxazolidin-2-ones and Applications for Synthesis of <i>α</i>-Oxo Carboxylic Acids

Yasushi Imada, Yo Mitsue, Kazuo Ike et al. · Bulletin of the Chemical Society of Japan · 1996 · 56 citations

Asymmetric Catalysis, Engineering, Biochemistry +14

Discovery of a Novel Series of Biphenyl Benzoic Acid Derivatives as Potent and Selective Human β₃-Adrenergic Receptor Agonists with Good Oral Bioavailability. Part I

Masashi Imanishi, Yasuyo Tomishima, Shinji Itou et al. · Journal of Medicinal Chemistry · 2008 · 41 citations

Novel generation and cycloaddition of N-silylated azomethine ylides from α-silylimidates and trifluorosilane

Kenichi Washizuka, Satoshi Minakata, Ilhyong Ryu et al. · Tetrahedron · 1999 · 40 citations

Novel Generation, Combinatorial Chemistry, Engineering +6

Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer

Fumiyuki Shirai, Anna Mizutani, Yoko Yashiroda et al. · Journal of Medicinal Chemistry · 2020 · 40 citations · Full text

Pharmacotherapy, Cancer Biology, Tumor Biology +16