Robert J. Aversa

USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin

Lei Ji, Bo Lü, Raffaella Zamponi et al. · Nature Communications · 2019 · 124 citations · Full text

Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin

K. C. Nicolaou, Michael O. Frederick, Antonio C. B. Burtoloso et al. · Journal of the American Chemical Society · 2008 · 81 citations

Chemical Synthesis of the GHIJK Ring System and Further Experimental Support for the Originally Assigned Structure of Maitotoxin

K. C. Nicolaou, Kevin P. Cole, Michael O. Frederick et al. · Angewandte Chemie International Edition · 2007 · 75 citations

Combinatorial Chemistry, Bioorganic Chemistry, Molecular Biology +20

Synthesis of the ABCDEFG Ring System of Maitotoxin

K. C. Nicolaou, Robert J. Aversa, Jian Jin et al. · Journal of the American Chemical Society · 2010 · 72 citations

Design and Discovery of <i>N</i>-(2-Methyl-5′-morpholino-6′-((tetrahydro-2<i>H</i>-pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

Gisele Nishiguchi, Alice Rico, Huw R. Tanner et al. · Journal of Medicinal Chemistry · 2017 · 44 citations · Full text

Drug Target, Kras Mutant Tumors, Kinase Inhibitors +17