Ryan O’Rourke

Genetic and transcriptional evolution alters cancer cell line drug response

Uri Ben‐David, Benjamin A. Siranosian, Gavin Ha et al. · Nature · 2018 · 890 citations · Full text

Tumor Heterogeneity, Medicine, Oncogenic Agent +9

SvABA: genome-wide detection of structural variants and indels by local assembly

Jeremiah A. Wala, Pratiti Bandopadhayay, Noah F. Greenwald et al. · Genome Research · 2018 · 455 citations · Full text

Structural Variants, Real Cancer Genomes, Genetics +21

Potential role of chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) in neurodegeneration and Alzheimer's disease

Kevin Connolly, Mikael Lehoux, Ryan O’Rourke et al. · Alzheimer s & Dementia · 2022 · 138 citations · Full text

Chitinase‐3‐like Protein 1, Molecular Biology, Cell Death +23

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors

Shakti Ramkissoon, Pratiti Bandopadhayay, Jaeho Hwang et al. · Neuro-Oncology · 2016 · 78 citations · Full text

SvABA: Genome-wide detection of structural variants and indels by local assembly

Jeremiah A. Wala, Pratiti Bandopadhayay, Noah F. Greenwald et al. · 2017 · 58 citations · Full text

Structural Variants, Real Cancer Genomes, Genetics +20